Most rushing yards in a team's first 4 games of an NFL season
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O.J. Simpson leads with 697 rushing yards through BUF's first 4 games of 1975, first of 25,235 player-seasons.
| # | Player and seasons | Value |
|---|---|---|
 O.J. Simpson (1975 BUF)1975 | 697 | |
| O.J. Simpson (1973 BUF)1973 | 647 | |
 Jamal Lewis (2003 BAL)2003 | 611 | |
 Stephen Davis (2003 CAR)2003 | 565 | |
 Emmitt Smith (1995 DAL)1995 | 543 | |
 Billy Sims (1980 DET)1980 | 539 | |
 Arian Foster (2010 HOU)2010 | 537 | |
 Kenneth Walker III (2026 KC)2026 | 537 | |
| DeMarco Murray (2014 DAL)2014 | 534 | |
 Terrell Davis (1997 DEN)1997 | 526 | |
 Derrick Henry (2021 TEN)2021 | 510 | |
 LaDainian Tomlinson (2002 LAC)2002 | 506 | |
 Curtis Martin (2004 NYJ)2004 | 502 | |
| Kareem Hunt (2017 KC)2017 | 502 | |
 James Wilder (1985 TB)1985 | 497 | |
 Bijan Robinson (2026 ATL)2026 | 494 | |
| Earl Campbell (1979 TEN)1979 | 493 | |
| Tony Dorsett (1981 DAL)1981 | 493 | |
| Terrell Davis (1998 DEN)1998 | 489 | |
 Walter Payton (1979 CHI)1979 | 484 | |
| Gerald Riggs (1984 ATL)1984 | 483 | |
 Adrian Peterson (2010 MIN)2010 | 480 | |
| Derrick Henry (2024 BAL)2024 | 480 | |
| Priest Holmes (2004 KC)2004 | 476 | |
 Curtis Martin (1997 NE)1997 | 474 |