Most sacks in an NFL defensive lineman's season
, , , .
Myles Garrett leads with 23 sacks in 2025, first of 11,150 defensive lineman seasons.
| # | Player and seasons | Value |
|---|---|---|
 Myles Garrett (2025 CLE)2025 | 23 | |
 Michael Strahan (2001 NYG)2001 | 22.5 | |
 Mark Gastineau (1984 NYJ)1984 | 22 | |
 Jared Allen (2011 MIN)2011 | 22 | |
 Reggie White (1987 PHI)1987 | 21 | |
| Chris Doleman (1989 MIN)1989 | 21 | |
 J.J. Watt (2012 HOU)2012 | 20.5 | |
| J.J. Watt (2014 HOU)2014 | 20.5 | |
 Aaron Donald (2018 LA)2018 | 20.5 | |
 Aldon Smith (2012 SF)2012 | 19.5 | |
| Mark Gastineau (1983 NYJ)1983 | 19 | |
 Bruce Smith (1990 BUF)1990 | 19 | |
| Clyde Simmons (1992 PHI)1992 | 19 | |
| Robert Quinn (2013 LA)2013 | 19 | |
 Chandler Jones (2019 ARI)2019 | 19 | |
 Dexter Manley (1986 WAS)1986 | 18.5 | |
 Robert Quinn (2021 CHI)2021 | 18.5 | |
| Nick Bosa (2022 SF)2022 | 18.5 | |
| Reggie White (1986 PHI)1986 | 18 | |
| Reggie White (1988 PHI)1988 | 18 | |
| Keith Millard (1989 MIN)1989 | 18 | |
| Michael Strahan (2003 NYG)2003 | 18 | |
| Jason Babin (2011 PHI)2011 | 18 | |
| Fred Dean (1983 SF)1983 | 17.5 | |
| Richard Dent (1984 CHI)1984 | 17.5 |