| Bruno Fernandes (2025-26 Manchester United)2025-26 | 21 |
| Cesc Fàbregas (2007-08 Arsenal)2007-08 | 20 |
| Kevin De Bruyne (2019-20 Manchester City)2019-20 | 20 |
| Mesut Özil (2015-16 Arsenal)2015-16 | 19 |
| Cesc Fàbregas (2014-15 Chelsea)2014-15 | 18 |
| Kevin De Bruyne (2016-17 Manchester City)2016-17 | 18 |
| Mohamed Salah (2024-25 Liverpool)2024-25 | 18 |
| Ashley Young (2007-08 Aston Villa)2007-081 of his appearances has no assists recorded, so the number is short. | 16 |
| Kevin De Bruyne (2017-18 Manchester City)2017-18 | 16 |
| Kevin De Bruyne (2022-23 Manchester City)2022-23 | 16 |
| Christian Eriksen (2016-17 Tottenham Hotspur)2016-17 | 15 |
| Leroy Sané (2017-18 Manchester City)2017-18 | 15 |
| Eden Hazard (2018-19 Chelsea)2018-19 | 15 |
| Cristiano Ronaldo (2006-07 Manchester United)2006-07 | 14 |
| Nani (2010-11 Manchester United)2010-11 | 14 |
| Ryan Fraser (2018-19 AFC Bournemouth)2018-19 | 14 |
| Harry Kane (2020-21 Tottenham Hotspur)2020-21 | 14 |
| Ollie Watkins (2023-24 Aston Villa)2023-24 | 14 |
| Cesc Fàbregas (2006-07 Arsenal)2006-07 | 13 |
| Mikel Arteta (2006-07 Everton)2006-07 | 13 |
| Wayne Rooney (2007-08 Manchester United)2007-081 of his appearances has no assists recorded, so the number is short. | 13 |
| Cesc Fàbregas (2009-10 Arsenal)2009-10 | 13 |
| Frank Lampard (2009-10 Chelsea)2009-101 of his appearances has no assists recorded, so the number is short. | 13 |
| Didier Drogba (2010-11 Chelsea)2010-11 | 13 |
| Steven Gerrard (2013-14 Liverpool)2013-14 | 13 |