| 1 | Wilt Chamberlain (1962-63 SFW) | 1962-63 | 529 |
| 2 | Wilt Chamberlain (1961-62 PHW) | 1961-62 | 496 |
| 3 | Rick Barry (1966-67 SFW) | 1966-67 | 381 |
| 4 | James Harden (2019-20 HOU) | 2019-20 | 373 |
| 5 | Wilt Chamberlain (1959-60 PHW) | 1959-60 | 371 |
| T6 | Michael Jordan (1986-87 CHI) | 1986-87 | 369 |
| T6 | Michael Jordan (1988-89 CHI) | 1988-89 | 369 |
| 8 | Elgin Baylor (1959-60 MNL) | 1959-60 | 364 |
| 9 | Jack Twyman (1959-60 CIN) | 1959-60 | 359 |
| 10 | Wilt Chamberlain (1960-61 PHW) | 1960-61 | 353 |
| 11 | Luka Dončić (2022-23 DAL) | 2022-23 | 348 |
| T12 | Elgin Baylor (1961-62 LAL) | 1961-62 | 344 |
| T12 | Kareem Abdul-Jabbar (1970-71 MIL) | 1970-71 | 344 |
| 14 | Walt Bellamy (1962-63 CHZ) | 1962-63 | 340 |
| T15 | Michael Jordan (1987-88 CHI) | 1987-88 | 338 |
| T15 | Michael Jordan (1992-93 CHI) | 1992-93 | 338 |
| 17 | Stephen Curry (2015-16 GSW) | 2015-16 | 333 |
| T18 | DeMar DeRozan (2016-17 TOR) | 2016-17 | 332 |
| T18 | Tyrese Maxey (2025-26 PHI) | 2025-26 | 332 |
| 20 | Joel Embiid (2023-24 PHI) | 2023-24 | 331 |
| T21 | Damian Lillard (2019-20 POR) | 2019-20 | 330 |
| T21 | George Gervin (1978-79 SAS) | 1978-79 | 330 |
| T21 | Kobe Bryant (2005-06 LAL) | 2005-06 | 330 |
| T21 | Shai Gilgeous-Alexander (2025-26 OKC) | 2025-26 | 330 |
| 25 | Michael Jordan (1989-90 CHI) | 1989-90 | 329 |