| Bijan Robinson2020 – 2022 | 2,475 |
| D'Onta Foreman2014 – 2016 | 2,368 |
| Jamaal Charles2005 – 2006 | 1,709 |
| Johnathan Gray2012 – 2014 | 1,659 |
| Jonathon Brooks2021 – 2023inactive after 17 games | 1,479 |
| Quintrevion Wisner2023 – 2025 | 1,475 |
| Keaontay Ingram2018 – 2019 | 1,453 |
| Malcolm Brown2011 – 2013 | 1,419 |
| Chris Warren2015 – 2017inactive after 24 games | 1,150 |
| Joe Bergeron2011 – 2013 | 1,136 |
| Roschon Johnson2019 – 2021 | 1,097 |
| Jaydon Blue2022 – 2024 | 993 |
| Sam Ehlinger2017 – 2019 | 961 |
| CJ Baxter2023 – 202521 of 25 games | 855 |
| Tre Watson2018inactive after 14 games | 786 |
| Tre' Newton2009 – 2010inactive after 19 games | 781 |
| Fozzy Whittaker2008 – 2010 | 760 |
| Vondrell McGee2007 – 2009 | 743 |
| Cody Johnson2008 – 2009 | 673 |
| Tyrone Swoopes2013 – 2015 | 607 |
| Jerrod Heard2015 – 2017 | 598 |
| Colt McCoy2006 – 2007 | 578 |
| Jerrick Gibson2024 – 202516 of 25 games | 529 |
| Arch Manning2023 – 2026 | 520 |
| D.J. Monroe2009 – 2011 | 456 |
| Raleek Brown20268 of 25 games | 452 |
| Daje Johnson2012 – 2014 | 431 |
| Keilan Robinson2021 – 2023 | 417 |
| John Chiles2007 – 2009 | 351 |
| Hollywood Smothers20266 of 25 games | 283 |
| David Ash2011 – 2012 | 244 |
| Christian Clark20258 of 25 games | 236 |
| Chris Ogbonnaya2005 – 2007 | 224 |
| James Simon2025 – 20266 of 25 games | 146 |
| Ryan Wingo2024 – 2025 | 142 |